If you implement a rule to quarantine messages bearing attachments named
then you will trap most of them although the false positive rate is relatively high (c. 5% here) so you can't just delete them. Not unreasonably, real people do occasionally send PDF attachments with either a period or an underscore in the filename.
Conversely, I have one PDF spam sample here which does not conform, to either pattern, though it is greatly outnumbered by those that do.

This one is named 08072007.pdf, presumably in honour of the date on which it was sent, and it is also a great deal prettier than those others.
Category: Spam characteristics
Technorati: PDF Pump+and+Dump Spam Image+Spam
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